2024
PLUS-IS-LESS project: Procalcitonin and Lung UltraSonography-based antibiotherapy in patients with Lower rESpiratory tract infection in Swiss Emergency Departments: study protocol for a pragmatic stepped-wedge cluster-randomized trial
Bessat C, Bingisser R, Schwendinger M, Bulaty T, Fournier Y, Della Santa V, Pfeil M, Schwab D, Leuppi J, Geigy N, Steuer S, Roos F, Christ M, Sirova A, Espejo T, Riedel H, Atzl A, Napieralski F, Marti J, Cisco G, Foley R, Schindler M, Hartley M, Fayet A, Garcia E, Locatelli I, Albrich W, Hugli O, Boillat-Blanco N. PLUS-IS-LESS project: Procalcitonin and Lung UltraSonography-based antibiotherapy in patients with Lower rESpiratory tract infection in Swiss Emergency Departments: study protocol for a pragmatic stepped-wedge cluster-randomized trial. Trials 2024, 25: 86. PMID: 38273319, PMCID: PMC10809691, DOI: 10.1186/s13063-023-07795-y.
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2023
Safety and immunogenicity of a synthetic nanoparticle-based, T cell priming peptide vaccine against dengue in healthy adults in Switzerland: a double-blind, randomized, vehicle-controlled, phase 1 study
Miauton A, Audran R, Besson J, Hajjami H, Karlen M, Warpelin-Decrausaz L, Sene L, Schaufelberger S, Faivre V, Faouzi M, Hartley M, Spertini F, Genton B. Safety and immunogenicity of a synthetic nanoparticle-based, T cell priming peptide vaccine against dengue in healthy adults in Switzerland: a double-blind, randomized, vehicle-controlled, phase 1 study. EBioMedicine 2023, 99: 104922. PMID: 38128414, PMCID: PMC10776924, DOI: 10.1016/j.ebiom.2023.104922.
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Modular Clinical Decision Support Networks (MoDN)—Updatable, interpretable, and portable predictions for evolving clinical environments
Trottet C, Vogels T, Keitel K, Kulinkina A, Tan R, Cobuccio L, Jaggi M, Hartley M. Modular Clinical Decision Support Networks (MoDN)—Updatable, interpretable, and portable predictions for evolving clinical environments. PLOS Digital Health 2023, 2: e0000108. PMID: 37459285, PMCID: PMC10351690, DOI: 10.1371/journal.pdig.0000108.
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Barriers and facilitators to implementation of point-of-care lung ultrasonography in a tertiary centre in Benin: a qualitative study among general physicians and pneumologists
Suttels V, Da Costa S, Garcia E, Brahier T, Hartley M, Agodokpessi G, Wachinou P, Fasseur F, Boillat-Blanco N. Barriers and facilitators to implementation of point-of-care lung ultrasonography in a tertiary centre in Benin: a qualitative study among general physicians and pneumologists. BMJ Open 2023, 13: e070765. PMID: 37369423, PMCID: PMC10357755, DOI: 10.1136/bmjopen-2022-070765.
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DeepBreath—automated detection of respiratory pathology from lung auscultation in 572 pediatric outpatients across 5 countries
Heitmann J, Glangetas A, Doenz J, Dervaux J, Shama D, Garcia D, Benissa M, Cantais A, Perez A, Müller D, Chavdarova T, Ruchonnet-Metrailler I, Siebert J, Lacroix L, Jaggi M, Gervaix A, Hartley M. DeepBreath—automated detection of respiratory pathology from lung auscultation in 572 pediatric outpatients across 5 countries. Npj Digital Medicine 2023, 6: 104. PMID: 37268730, PMCID: PMC10238513, DOI: 10.1038/s41746-023-00838-3.
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ePOCT+ and the medAL-suite: Development of an electronic clinical decision support algorithm and digital platform for pediatric outpatients in low- and middle-income countries
Tan R, Cobuccio L, Beynon F, Levine G, Vaezipour N, Luwanda L, Mangu C, Vonlanthen A, De Santis O, Salim N, Manji K, Naburi H, Chirande L, Matata L, Bulongeleje M, Moshiro R, Miheso A, Arimi P, Ndiaye O, Faye M, Thiongane A, Awasthi S, Sharma K, Kumar G, Van De Maat J, Kulinkina A, Rwandarwacu V, Dusengumuremyi T, Nkuranga J, Rusingiza E, Tuyisenge L, Hartley M, Faivre V, Thabard J, Keitel K, D’Acremont V. ePOCT+ and the medAL-suite: Development of an electronic clinical decision support algorithm and digital platform for pediatric outpatients in low- and middle-income countries. PLOS Digital Health 2023, 2: e0000170. PMID: 36812607, PMCID: PMC9931356, DOI: 10.1371/journal.pdig.0000170.
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2022
What If…? Pandemic policy-decision-support to guide a cost-benefit-optimised, country-specific response
Mannarini G, Posa F, Bossy T, Massemin L, Fernandez-Castanon J, Chavdarova T, Cañas P, Gupta P, Jaggi M, Hartley M. What If…? Pandemic policy-decision-support to guide a cost-benefit-optimised, country-specific response. PLOS Global Public Health 2022, 2: e0000721. PMID: 36962770, PMCID: PMC10022143, DOI: 10.1371/journal.pgph.0000721.
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Genomic Diversity of Torque Teno Virus in Blood Samples from Febrile Paediatric Outpatients in Tanzania: A Descriptive Cohort Study
Laubscher F, Hartley M, Kaiser L, Cordey S. Genomic Diversity of Torque Teno Virus in Blood Samples from Febrile Paediatric Outpatients in Tanzania: A Descriptive Cohort Study. Viruses 2022, 14: 1612. PMID: 35893678, PMCID: PMC9330782, DOI: 10.3390/v14081612.
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Point-of-care ultrasound for tuberculosis management in Sub-Saharan Africa—a balanced SWOT analysis
Suttels V, Du Toit J, Fiogbé A, Wachinou A, Guendehou B, Alovokpinhou F, Toukoui P, Hada A, Sefou F, Vinasse P, Makpemikpa G, Capo-Chichi D, Garcia E, Brahier T, Keitel K, Ouattara K, Cissoko Y, Beye S, Mans P, Agodokpessi G, Boillat-Blanco N, Hartley M. Point-of-care ultrasound for tuberculosis management in Sub-Saharan Africa—a balanced SWOT analysis. International Journal Of Infectious Diseases 2022, 123: 46-51. PMID: 35811083, DOI: 10.1016/j.ijid.2022.07.009.
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Point-of-care lung ultrasonography for early identification of mild COVID-19: a prospective cohort of outpatients in a Swiss screening center
Schaad S, Brahier T, Hartley M, Cordonnier J, Bosso L, Espejo T, Pantet O, Hugli O, Carron P, Meuwly J, Boillat-Blanco N. Point-of-care lung ultrasonography for early identification of mild COVID-19: a prospective cohort of outpatients in a Swiss screening center. BMJ Open 2022, 12: e060181. PMID: 35750462, PMCID: PMC9234434, DOI: 10.1136/bmjopen-2021-060181.
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Ultrasound for point-of-care sputum-free tuberculosis detection: Building collaborative standardized image-banks
Suttels V, Wachinou P, Du Toit J, Boillat-Blanco N, Hartley M. Ultrasound for point-of-care sputum-free tuberculosis detection: Building collaborative standardized image-banks. EBioMedicine 2022, 81: 104078. PMID: 35649304, PMCID: PMC9160315, DOI: 10.1016/j.ebiom.2022.104078.
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2021
Blood virosphere in febrile Tanzanian children
Cordey S, Laubscher F, Hartley M, Junier T, Keitel K, Docquier M, Guex N, Iseli C, Vieille G, Le Mercier P, Gleizes A, Samaka J, Mlaganile T, Kagoro F, Masimba J, Said Z, Temba H, Elbanna G, Tapparel C, Zanella M, Xenarios I, Fellay J, D’Acremont V, Kaiser L. Blood virosphere in febrile Tanzanian children. Emerging Microbes & Infections 2021, 10: 982-993. PMID: 33929935, PMCID: PMC8171259, DOI: 10.1080/22221751.2021.1925161.
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2020
Weight Erosion: An Update Aggregation Scheme for Personalized Collaborative Machine Learning
Grimberg F, Hartley M, Jaggi M, Karimireddy S. Weight Erosion: An Update Aggregation Scheme for Personalized Collaborative Machine Learning. Lecture Notes In Computer Science 2020, 12444: 160-169. DOI: 10.1007/978-3-030-60548-3_16.
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Clinical relevance of low-density Plasmodium falciparum parasitemia in untreated febrile children: A cohort study
Hartley M, Hofmann N, Keitel K, Kagoro F, Moniz C, Mlaganile T, Samaka J, Masimba J, Said Z, Temba H, Gonzalez I, Felger I, Genton B, D’Acremont V. Clinical relevance of low-density Plasmodium falciparum parasitemia in untreated febrile children: A cohort study. PLOS Medicine 2020, 17: e1003318. PMID: 32956354, PMCID: PMC7505590, DOI: 10.1371/journal.pmed.1003318.
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Lung Ultrasonography for Risk Stratification in Patients with Coronavirus Disease 2019 (COVID-19): A Prospective Observational Cohort Study
Brahier T, Meuwly J, Pantet O, Vez M, Donnet H, Hartley M, Hugli O, Boillat-Blanco N. Lung Ultrasonography for Risk Stratification in Patients with Coronavirus Disease 2019 (COVID-19): A Prospective Observational Cohort Study. Clinical Infectious Diseases 2020, 73: e4189-e4196. PMID: 32940646, PMCID: PMC7543331, DOI: 10.1093/cid/ciaa1408.
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Precision global health: a roadmap for augmented action
Sheath D, de Castañeda R, Bempong N, Raviglione M, Machalaba C, Pepper M, Vayena E, Ray N, Wernli D, Escher G, Grey F, Elger B, Helbing D, Kleineberg K, Beran D, Miranda J, Huffman M, Hersch F, Andayi F, Thumbi S, D’Acremont V, Hartley M, Zinsstag J, Larus J, Martínez M, Guerin P, Merson L, Ngyuen V, Rühli F, Geissbuhler A, Salathé M, Bolon I, Boehme C, Berkley S, Valleron A, Keiser O, Kaiser L, Eckerle I, Utzinger J, Flahault A. Precision global health: a roadmap for augmented action. Journal Of Public Health And Emergency 2020, 4: 5-5. DOI: 10.21037/jphe.2020.01.01.
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2019
Nearly Complete Genome Sequence of a Novel Phlebovirus-Like Virus Detected in a Human Plasma Sample by High-Throughput Sequencing
Laubscher F, Cordey S, Hartley M, Vieille G, Boillat-Blanco N, Samaka J, Mlaganile T, d’Acremont V, Kaiser L. Nearly Complete Genome Sequence of a Novel Phlebovirus-Like Virus Detected in a Human Plasma Sample by High-Throughput Sequencing. Microbiology Resource Announcements 2019, 8: 10.1128/mra.00764-19. PMID: 31467101, PMCID: PMC6715871, DOI: 10.1128/mra.00764-19.
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Machine-learning Prognostic Models from the 2014–16 Ebola Outbreak: Data-harmonization Challenges, Validation Strategies, and mHealth Applications
Colubri A, Hartley M, Siakor M, Wolfman V, Felix A, Sesay T, Shaffer J, Garry R, Grant D, Levine A, Sabeti P. Machine-learning Prognostic Models from the 2014–16 Ebola Outbreak: Data-harmonization Challenges, Validation Strategies, and mHealth Applications. EClinicalMedicine 2019, 11: 54-64. PMID: 31312805, PMCID: PMC6610774, DOI: 10.1016/j.eclinm.2019.06.003.
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Detection of dicistroviruses RNA in blood of febrile Tanzanian children
Cordey S, Laubscher F, Hartley M, Junier T, Pérez-Rodriguez F, Keitel K, Vieille G, Samaka J, Mlaganile T, Kagoro F, Boillat-Blanco N, Mbarack Z, Docquier M, Brito F, Eibach D, May J, Sothmann P, Aldrich C, Lusingu J, Tapparel C, D’Acremont V, Kaiser L. Detection of dicistroviruses RNA in blood of febrile Tanzanian children. Emerging Microbes & Infections 2019, 8: 613-623. PMID: 30999808, PMCID: PMC6493270, DOI: 10.1080/22221751.2019.1603791.
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2018
<i>Leishmania guyanensis</i> parasites block the activation of the inflammasome by inhibiting maturation of IL-1β
Hartley M, Eren R, Rossi M, Prevel F, Castiglioni P, Isorce N, Desponds C, Lye L, Beverley S, Drexler S, Fasel N. Leishmania guyanensis parasites block the activation of the inflammasome by inhibiting maturation of IL-1β. Microbial Cell 2018, 5: 137. PMID: 29487860, PMCID: PMC5826701, DOI: 10.15698/mic2018.03.619.
Peer-Reviewed Original Research
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